Microtubule chemical complexity: mechanism of tubulin modification enzymes
نویسندگان
چکیده
منابع مشابه
Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation.
Microtubules (MTs) are dynamic structures that are fundamental for cell morphogenesis and motility. MT-associated motors work efficiently to perform their functions. Unlike other motile kinesins, KIF2 catalytically depolymerizes MTs from the peeled protofilament end during ATP hydrolysis. However, the detailed mechanism by which KIF2 drives processive MT depolymerization remains unknown. To elu...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances
سال: 2014
ISSN: 2053-2733
DOI: 10.1107/s2053273314087130